Scientific Publications

SKINTEGRITY.CH Principal Investigators are underlined

2020

Bircher, K., Merluzzi, R., Wahlsten, A., Spiess, D., Simoes-Wust, A. P., Ochsenbein-Kolble, N., Zimmermann, R., Deprest J., & Mazza, E. (2020). Influence of osmolarity and hydration on the tear resistance of the human amniotic membrane. J Biomech, 98, 109419. doi:10.1016/j.jbiomech.2019.109419

Cangkrama, M., Wietecha, M., Mathis, N., Okumura, R., Ferrarese, L., Al-Nuaimi, D., Antsiferova, M., Dummer, R., Innocenti, M., & Werner, S. (2020). A paracrine activin A-mDia2 axis promotes squamous carcinogenesis via fibroblast reprogramming. EMBO Mol Med, 12(4), e11466. doi:10.15252/emmm.201911466

Hennig, P., Fenini, G., Di Filippo, M., & Beer, H. D. (2020). Electrophiles Against (Skin) Diseases: More Than Nrf2. Biomolecules, 10(2). doi:10.3390/biom10020271

Hettich, B. F., Ben‐Yehuda, M., Werner, S., Leroux, J.‐C., Exosomes for Wound Healing: Purification Optimization and Identification of Bioactive Components. Adv. Sci. 2020, 2002596. doi:10.1002/advs.202002596

McLuckie, M., Robotti, F., Sanchez-Macedo, N., Enderlin, D., Frese, L., Cheng, P. F., Levesque, M.P., Egana, J.T., Poulikakos, D., Ferrari, A., & Lindenblatt, N. (2020). Lipoconstruct surface topography grating size influences vascularization onset in the dorsal skinfold chamber model. Acta Biomater. doi:10.1016/j.actbio.2020.01.050

Mueller, B., Elrod, J., Distler, O., Schiestl, C., & Mazza, E. (2020). On the Reliability of Suction Measurements for Skin Characterization. ASME. J Biomech Eng. February 2021; 143(2): 021002. doi: 10.1115/1.4047661

Mueller, B., Ruby, L., Jordan, S., Rominger M., Mazza, E. & Distler, O. (2020) Validation of the suction device Nimble for the assessment of skin fibrosis in systemic sclerosis. Arthritis Res Ther 22, 128 (2020).  doi: 10.1186/s13075-020-02214-y

2019

Elrod, J., Muller, B., Mohr, C., Meuli, M., Mazza, E., & Schiestl, C. (2019). An effective procedure for skin stiffness measurement to improve Paediatric Burn Care. Burns, 45(5), 1102-1111. doi:10.1016/j.burns.2019.02.004

Fox, S., Polak, J., Schmid Daners, M., & Meboldt, M. (2019). Fabrication of Bioengineered Skin by Injection Molding: A Feasibility Study on Automation. SLAS Technol, 24(5), 506-514. doi:10.1177/2472630319857966

Fox, S., Biedermann, T., Polak, J., Reichmann, E., Daners, M. S., & Meboldt, M. (2019). A simplified fabrication technique for cellularized high-collagen dermal equivalents. Biomed Mater, 14(4), 041001. doi:10.1088/1748-605X/ab09c5

Fox, S. C., Siallagan, D., Schmid Daners, M., & Meboldt, M. (2019). Rethinking automated skin fabrication for regeneration: adapting to commercial challenges. Curr Opin Biomed Engin, 10, 165-173. doi:10.1016/j.cobme.2019.07.001

Matei, A. E., Chen, C. W., Kiesewetter, L., Gyorfi, A. H., Li, Y. N., Trinh-Minh, T., Xu, X., Tran Manh, C., van Kuppevelt, T., Hansmann, J., Jüngel, A., Schett, G., Groeber-Becker, F., &. Distler, J. H. W. (2019). Vascularised human skin equivalents as a novel in vitro model of skin fibrosis and platform for testing of antifibrotic drugs. Ann Rheum Dis, 78(12), 1686-1692. doi:10.1136/annrheumdis-2019-216108

Michalak-Micka, K., Klar, A. S., Bottcher-Haberzeth, S., Reichmann, E., Meuli, M., & Biedermann, T. (2019). Impact of human mesenchymal cells of different body site origins on the maturation of dermo-epidermal skin substitutes. Pediatr Surg Int, 35(1), 121-127. doi:10.1007/s00383-018-4383-5

Morel, A., Oberle, S. C., Ulrich, S., Yazgan, G., Spano, F., Ferguson, S. J., .Fortunato, G. & Rossi, R. M. (2019). Revealing non-crystalline polymer superstructures within electrospun fibers through solvent-induced phase rearrangements. Nanoscale, 11(36), 16788-16800. doi:10.1039/c9nr04432a

Polomska, A. K., Proulx, S. T., Brambilla, D., Fehr, D., Bonmarin, M., Brandli, S., Meboldt, M., Steuer, C, Vasileva T., Reinke, N., Leroux, J.C. &. Detmar, M. (2019). Minimally invasive method for the point-of-care quantification of lymphatic vessel function. JCI Insight, 4(4). doi:10.1172/jci.insight.126515

Tuncer E, Calçada RC, Zingg D, Varum S, Cheng P, Freiberger SN, Deng C-X, Kleiter I, Levesque MP, Dummer R, and Sommer L (2019). SMAD signaling promotes melanoma metastasis independently of phenotype switching. J. Clin. Invest., 129:2702-2716. doi: 10.1172/JCI94295

Varum S, Baggiolini A Zurkirchen L, Kalender Atak Z, CantùC, Marzorati E, Bossart R, Wouters J, Häusel J, Tuncer E, Zingg D, Veen D, John N, Balz M, Levesque MP, Basler K, Aerts S, Zamboni N, Dummer R and Sommer L (2019). Yin Yang 1 orchestrates a metabolic program required for both neural crest development and melanoma formation. Cell Stem Cell, 24:637-653. doi: 10.1016/j.stem.2019.03.011

Wahlsten, A., Pensalfini, M., Stracuzzi, A., Restivo, G., Hopf, R., & Mazza, E. (2019). On the compressibility and poroelasticity of human and murine skin. Biomech Model Mechanobiol, 18(4), 1079-1093. doi:10.1007/s10237-019-01129-1

2018

Muller, B., Elrod, J., Pensalfini, M., Hopf, R., Distler, O., Schiestl, C., & Mazza, E. (2018). A novel ultra-light suction device for mechanical characterization of skin. PLoS One, 13(8), e0201440. doi:10.1371/journal.pone.0201440

Parfejevs, V., Debbache, J., Shakhova, O., Schaefer, S. M., Glausch, M., Wegner, M., Suter, U., Riekstina, U., Werner, S., & Sommer, L. (2018). Injury-activated glial cells promote wound healing of the adult skin in mice. Nat Commun, 9, 236. doi:10.1038/s41467-017-01488-2

Pensalfini, M., Meneghello, S., Lintas, V., Bircher, K., Ehret, A. E., & Mazza, E. (2018). The suture retention test, revisited and revised. J Mech Behav of Biomed, 77, 711-717. doi:10.1016/j.jmbbm.2017.08.021

Pensalfini, M., Weickenmeier, J., Rominger, M., Santoprete, R., Distler, O., & Mazza, E. (2018). Location-specific mechanical response and morphology of facial soft tissues. J Mech Behav of Biomed, 78, 108-115. doi:10.1016/j.jmbbm.2017.10.021

Randall, M. J., Jungel, A., Rimann, M., & Wuertz-Kozak, K. (2018). Advances in the Biofabrication of 3D Skin in vitro: Healthy and Pathological Models. Front Bioeng Biotechnol, 6, 154. doi:10.3389/fbioe.2018.00154

Zingg D, Debbache J, Peña-Hernández R, Antunes AT, Schaefer SM, Cheng PF, Zimmerli D, Haeusel J, Calçada RR, Tuncer E, Zhang Y, Bossart R, Wong KK, Basler K, Dummer R, Santoro R, Levesque MP, Sommer L (2018). EZH2-mediated primary cilium deconstruction drives metastatic melanoma formation. Cancer Cell 34: 69-84. doi: 10.1016/j.ccell.2018.06.00 Highlighted in the same issue: Jackson PK (2018): EZH2 inactivates primary cilia to activate Wnt and drive melanoma. Cancer Cell 34: 3-5.

2017

Klar, A. S., Biedermann, T., Michalak, K., Michalczyk, T., Meuli-Simmen, C., Scherberich, A., Meuli, M., and Reichmann, E. (2017). Human Adipose Mesenchymal Cells Inhibit Melanocyte Differentiation and the Pigmentation of Human Skin via Increased Expression of TGF-beta1. J Invest Dermatol, 137(12), 2560-2569. doi:10.1016/j.jid.2017.06.027

Pensalfini, M., Haertel, E., Hopf, R., Wietecha, M., Werner, S., & Mazza, E. (2017). The mechanical fingerprint of murine excisional wounds. Acta Biomaterialia, 1-11. doi:10.1016/j.actbio.2017.10.021