Chronic disease often leads to fibrosis, a condition in which organ tissue suffers from excessive scarring. In a great collaboration, SKINTEGRITY.CH PI Prof. Christian Stockmann at the University of Zurich and an international team of colleagues (including our PIs Profs. Oliver Distler, Lukas Sommer and Sabine Werner as well as the Young Investigators Jing Chen, Zheng Fan and Elena Pachera) developed an immunotherapy that specifically targets the cause – activated fibroblasts – while leaving normal connective tissue cells unharmed. If this approach is also found to work in humans, it could lead to an effective treatment for fibrosis.
Read the full press release or the scientific publication in Cell Stem Cell.
(In the image: air-filled alveoli in healthy lung tissue on the left, versus fibrotic tissue on the right. © Christian Stockmann)